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Off-the-shelf drug reduces skin inflammation in animal models and human cell culture

Association believed to be related to inflammation

PD-1/PD-L1 inhibitors singled out for association

A 38-year-old woman visited her doctor about itchy, raised spots that developed on her fingers 5 days prior. Can you diagnose the patient?

But only a minority achieved minimal disease activity within 16 weeks

Prices slashed by as much as 79%

More than 90% of patients met response criteria at 68 weeks with 8- or 16-week dosing

Poor air quality adds significantly to risk from genetic susceptibility factors

Previous exposure to biologics, higher BMI, smoking all negatively linked to response

Early phase III data cement case for novel IL-17A inhibitor

Studies may explain some cases of rare opportunistic infections

EULAR provides easy-to-understand algorithm

High response rates out to 52 weeks with IL-23 inhibitor, correlating with eradication of T cells

Noninferiority achieved across all skin subtypes