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General Rheumatology

News, opinions and meeting coverage in rheumatology.

A photo of a woman drawing from a vial of Remicade.

Medicare Lags, Medicaid Leads for Biosimilar Uptake

Infliximab copycat usage varies widely with payer type

A computer rendering of antibodies around a transparent brain with the basal ganglia highlighted.

Researchers Try to Better Understand PANS/PANDAS

Stanford University group suggests new component to long controversial diagnosis

A photo of a woman with alopecia areata.

Alopecia Areata Tied to Higher Risks of Autoimmune and Psychiatric Comorbidities

This could exacerbate disease burden and reduce quality of life, researchers say

Superior migration of humeral head

Make the Diagnosis: There are Lots of Clues, but Can You Make the Diagnosis?

A 68-year-old man presented to the doctor with complaints of right shoulder pain, joint stiffness, and decreased range of motion that developed over the last 2 months. Can you diagnose the patient?

A photo of row houses in Philadelphia.

Poor Neighborhood, More Than Race, Predicts Greater Lupus Skin Severity

Blackness, per se, seen as less important than area socioeconomics

A computer rendering of a transparent body with the kidneys highlighted.

This Drug Class Keeps AA Amyloidosis in Check

Staves off end-stage renal disease, retrospective study indicates

A photo of smog over London.

Genes, Air Pollution Combine to Raise Lupus Risk

British data suggest how environmental and genetic factors add together

A distorted Amsler grid over a photo of an eye.

Rheumatology Meds Seen Cutting AMD Risk

Claims data point to possible protective effect for one common drug class

A photo of a mature woman鈥檚 knee x-ray on a monitor as she meets with a female rheumatologist in the background.

Osteoarthritis Diagnosis Portends Sickly Later Life

20-year study portrays OA as risk factor for multiple comorbidity

A computer rendering of periodontitis.

Wait, Maybe Periodontal Disease Doesn't Promote Rheumatoid Arthritis (or Vice Versa)

Danish study suggests surprising explanation for association

A photo of a woman wearing an apron carrying a frozen pizza on a baking sheet.

Do Ultraprocessed Foods Increase Lupus Risk for Women?

Sobering findings from Nurses' Health Study

A photo of a man鈥檚 hand inflamed by systemic lupus erythematosus

Could Two Targeted Therapies Be Better Than One in Lupus?

Mid-stage trial tests a JAK inhibitor as monotherapy and in combination with a BTK blocker

A close up photo of broccoli soup.

Really, Soup Might Help in Osteoarthritis?

Not just any soup. And no chicken needed.

A photo of a prescription bottle of metformin tablets next to a glucose monitor.

Lupus Complications Reduced With Common Diabetes Drug

Metformin benefits seen extending way beyond its glucose-lowering properties

A computer rendering of test tubes of blood lying on a test form.

Use This Common Cardiac Test in RA Patients, Study Suggests

Identifies heart risks not captured by conventional risk factors

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

SpA Patients Do Just Fine Managing Their Own Follow-Up Care

Randomized trial suggests usual practice is wasteful

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Izokibep Marches on for Psoriatic Arthritis

Early phase III data cement case for novel IL-17A inhibitor

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Novel URAT1 Inhibitors Advance for Gout

New treatment options on the horizon come into better focus

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

OA Patients Get Long-Term Benefit From Lifestyle Improvements

Improvement in pain and function lasted well after formal program ended

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

Is 'Difficult-to-Treat' RA a Lost Cause?

The name says it all, but progress appears to be coming

EULAR over a photo of Vienna Exhibition Center in Vienna, Austria.

CAR-T Treatment Continues to Astonish in Rheumatologic Diseases

Numbers of patients, length of follow-up keep growing with no visible downside (yet)

A close up photo of a Humira prefilled syringe.

Humira Clobbers Biosimilars in Battle for Part D Coverage

Pricing, payer policies keep market leader on top

A photo of a bottle of Olumiant tablets.

JAK or TNF Inhibitor as First Targeted Drug for Rheumatoid Arthritis?

Pragmatic head-to-head study finds a winner, with caveats

A photo of a senior woman grimacing while clutching her painful wrist.

In RA, Poorly Controlled Pain Portends Even More Serious Problems

Australian study documents risks for life-threatening complications

A scanning electron microscope image of T cells.

Finally, a Treatment Emerges for Autoimmune Polyendocrine Syndrome

And it's on the pharmacy shelf now

A photo of a bottle of Olumiant tablets.

Not All COVID Patients Benefit From JAK Inhibitor

Post-hoc analysis shows that body weight makes an important difference

A photo of a senior man lying in a hospital bed and reading on a tablet.

Study Confirms: No Great Options for Treating VEXAS

Efficacy versus safety is the inevitable tradeoff, and efficacy isn't that good to begin with

A photo of Antarctic krill.

Krill Oil Fails in New Osteoarthritis Trial

Now the question is how to reconcile this study with others finding a benefit

A computer rendering of antibodies in the blood.

Doubt Cast on MGUS-Autoimmune Disease Link

Population-based study fails to confirm earlier findings

A photo of a foot swollen from gout.

Yet Another Benefit for Metformin?

Study suggests a surprising effect in rheumatologic disease risk

A photo of the tablet, container, and packaging of Rinvoq.

One-Year Data Back Upadacitinib for Clinical Spondyloarthritis

Adds to 14-week results that powered FDA approval for non-radiographic axial spondyloarthritis

A photo of a man receiving a knee injection by a male physician.

Stem Cell Injections in Mexico Led to Drug-Resistant Infections

Three patients acquired Mycobacterium abscessus infections after medical travel

A photo of a bottle of hydroxychloroquine tablets.

Retinopathy With Long-Term HCQ Use: Large Study IDs Risk Factors

Hint: it's not just the cumulative dose

A photo of a mother checking her daughter鈥檚 temperature.

How Does FMF Affect Adolescent Females? Study Offers New Details

And proposes a treatment algorithm to manage the disease in this population

A photo of a female radiologist performing temporal ultrasound of her senior male patient

Imaging-Only Diagnosis of Giant Cell Arteritis Is Feasible

Color Doppler ultrasound proves mettle as standalone method

A computer rendering of pliers extracting a tooth from a lower jaw.

Missing Teeth and Joint Pain? RA May Be Imminent

You may not even have to ask if patient has had periodontal disease

A photo of runners in the Brooklyn half and full Marathon in New York City.

Study: Skinny-Leg Runners Face Higher Rates of Knee Arthritis

Questions about risks from weight-bearing activities may now be settled

A close up photo of the hand of a person with systemic lupus erythematosus

Can Innate Immune System Be Targeted Directly in Lupus?

Japanese researchers open new front in SLE therapy

A photo of a mature man massaging his knee.

Hands-On Treatment May Help in Knee Osteoarthritis

And patients can administer it themselves

A photo of Kristin Fritz

'I Feel So Violated': Over 200 Patients Accuse Doc of Sex Abuse, Unnecessary Exams

Alleged victims included women and several men

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