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Multiple Sclerosis

News, opinions and meeting coverage in neurology.

Dalfampridine: Not Just a Walking Aid

DALLAS -- Extended-release dalfampridine (Ampyra) is approved for boosting walking speed in multiple sclerosis patients, but its benefits extend to other aspects of physical function, according to a small study reported here.

CCSVI Practices Suboptimal but Patients Don't Mind

DALLAS -- Canadian multiple sclerosis patients who left the country to undergo the controversial procedure called chronic cerebrospinal venous insufficiency (CCSVI) often received poor pre- and postoperative care, but most were still relatively satisfied overall, a researcher reported here.

Gastro Effects Dog Oral MS Drug Tecfidera

DALLAS -- Large proportions of patients starting on dimethyl fumarate (Tecfidera) for multiple sclerosis need additional medications to manage the drug's GI and other side effects, and a substantial minority ultimately find the drug intolerable.

MS Bladder Problems Show Up Early and Often

Nearly 80% of multiple sclerosis patients in a large registry reported overactive bladder symptoms, and one-third of a separate cohort of newly diagnosed patients also showed urinary dysfunction, researchers reported here.

Striking a Nerve: MS Cured With an OTC Drug?

A neurology researcher is planning a clinical trial of a widely available drug that he thinks could stave off disability in multiple sclerosis patients. How much should he (or we) say publicly about it?

Repeat Botox OK for Urinary Incontinence in MS Patients

COPENHAGEN -- Long-term treatment with serial onabotulinum toxin A (Botox) of urinary incontinence among multiple sclerosis (MS) patients appeared to be safe and effective, researchers reported here.

PML Not Fatal if Caught Early

SAN DIEGO - All multiple sclerosis patients taking natalizumab (Tysabri) who were diagnosed with a serious condition called PML before symptoms appeared were still alive a year later, researchers said.

New Guideline on Transverse Myelitis Released

Certain clinical, imaging, and laboratory findings can help determine the etiology and prognosis in patients presenting with transverse myelitis, according to a new guideline from the American Academy of Neurology.

MS Walking Drug Gets FDA Nod

WASHINGTON -- The FDA approved the first drug for improved walking in patients with multiple sclerosis, the tablet dalfampridine (Ampyra).

Blacks and Whites Have Different Immune Response to MS

ST. LOUIS -- African Americans with multiple sclerosis have a more robust immunologic response than whites, which may explain the greater severity of symptoms among blacks, investigators here found.

Tysabri (Natalizumab) Allowed Back to Market with Restrictions

ROCKVILLE, Md. — The FDA has cleared the way for Tysabri (natalizumab), the multiple sclerosis drug, to go back on the market but under a special restricted distribution program.

IBD Patients Prone to Other Autoimmune or Inflammatory Disorders

PHILADELPHIA-Patients with the inflammatory bowel disorders ulcerative colitis and Crohn's disease are significantly more likely to suffer from other conditions with an inflammatory or autoimmune basis, said researchers in two separate studies.