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Viagra and Alzheimer's; Migraine Consensus Statement; FDA Updates Drug Guidance

— News and commentary from the world of neurology and neuroscience

MedpageToday
Neuro Break over a computer rendering of neurons.

More data supported links between the (Viagra) and reduced Alzheimer's risk. (Journal of Alzheimer's Disease)

The American Headache Society issued a saying drugs targeting calcitonin gene-related peptide are a first-line option for migraine prevention. (Headache)

Eli Lilly said the FDA will to discuss the phase III TRAILBLAZER-ALZ 2 trial of investigational donanemab in early symptomatic Alzheimer's disease.

in cerebrospinal fluid were associated with non-relapsing MS. (JAMA Neurology)

A recently approved combination of sodium phenylbutyrate and taurursodiol (Relyvrio) in a confirmatory amyotrophic lateral sclerosis trial, Amylyx Pharmaceuticals said. The company may pull the drug from the market.

Cysticercosis -- infection -- presented as migraine in a 52-year-old man. (American Journal of Case Reports)

Merck KGaA dropped its investigational Bruton's tyrosine kinase after the drug failed to beat teriflunomide (Aubagio) in two phase III trials of multiple sclerosis. (Fierce Biotech)

The FDA for developing drugs to treat early Alzheimer's disease to include the agency's current thinking about biomarkers in clinical trials.

Functional MRI showed how the brain while filtering distraction. (Nature Human Behavior)

Nearly half of patients who used said it contributed to using less migraine medication. (Neurology)

  • Judy George covers neurology and neuroscience news for app, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more.