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General Nephrology

News, opinions and meeting coverage in nephrology.

A photo of the San Francisco skyline.

California Sets Long-Awaited Drinking Water Limit for 'Erin Brockovich' Contaminant

The rule is the first in the nation to specifically target the heavy metal

A photo of two bottles of risperidone tablets.

Antipsychotics in Dementia Tied to Wider Range of 'Serious Harms'

Steepest increases in risk observed for pneumonia, kidney injury, VTE, and stroke

A computer rendering of a transparent body with the kidneys highlighted.

TNF Inhibitors for IBD Linked to Kidney Function Declines

Observational VA data support recommendations for monitoring with initiation

A photo of a woman receiving dialysis in a clinic.

Multidisciplinary Team Intervention Flops for Improving CKD Outcomes

Intervention "did not overcome barriers" to PCP, patient behavior changes, editorialists say

A photo of a surgeon performing an intravitreal injection.

No Difference in Kidney Failure Risk Between Three Anti-VEGF Agents for Eye Disease

"We can let other factors guide our treatment," researcher says

A photo of a mature man receiving dialysis in a hospital.

Primary Care Strategy Fails to Reduce Kidney-Dysfunction Triad Hospitalizations

Secondary outcomes also showed no significant differences

FDA APPROVED vadadustat (Vafseo) over a photo of a woman receiving dialysis.

Once-Rejected Drug Now FDA Approved for CKD-Related Anemia

Indication for HIF-PH inhibitor vadadustat limited to patients already on dialysis

A photo of surgeons performing the pig kidney transplant.

First-Ever Pig Kidney Transplant Performed in Living Recipient

Patient with end-stage kidney disease underwent transplant at Massachusetts General Hospital

A photo of a stylist applying hair-straightening cream to her female client.

Acute Kidney Injury: The Price of Straight Hair?

Case study highlights dangers of glyoxylic acid-containing products

A computer rendering of chronic kidney disease

EHR Alerts Trigger Primary Care Clinics to Improve Hypertension Care in CKD

Greater reduction in systolic BP over usual care in randomized trial

A computer rendering of viruses in a transparent kidney.

Acute Kidney Injury Outcomes Better When It's Due to COVID, Study Finds

"Survivors of COVID-AKI appear to be a resilient population," say researchers

FDA APPROVED Selective cytopheretic device-pediatric (SCD-PED) over a computer rendering of diseased kidneys.

FDA OKs Device for Pediatric Kidney Injury Due to Sepsis

The device was granted a Humanitarian Device Exemption approval

CCC over a photo of Bellagio Hotel & Casino in Las Vegas, NV

History of IBD Linked to Severe Outcomes in Patients Hospitalized for COVID

IBD was associated with an increased risk of sepsis, shock, and acute kidney injury

A computer rendered cross section of kidneys with kidney stones

One Class of Antidiabetic Linked With Lower Kidney Stone Risk

Study compared SGLT2 inhibitors with GLP-1 agonists and DPP-4 inhibitors

A photo of a Fresenius Kidney Care center in Houston, Texas.

FDA Slams Fresenius Over Its Response to PCBs in Dialysis Machines

A 3-year saga raises questions about a potential class effect

A photo of Rep. Suzan DelBene (D-Wash.)

Q&A: Talking Prior Authorization With Rep. Suzan DelBene

The Washington congresswoman also discusses home dialysis, Medicare cuts

A photo of the Prolia auto injector and packaging.

FDA Slaps Boxed Warning on Osteoporosis Drug

Denosumab can cause severe hypocalcemia in patients with advanced CKD, agency finds

A computer rendered cutaway of a spine affected by osteoporosis

Calcium Levels Quickly Become Critical for Many Denosumab-Treated Women on Dialysis

New findings led to boxed warning on drug's labeling for advanced CKD patients

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Severe Stroke at Age 24; Nurses' $100,000 Bonus; Paxlovid Insider Trading Conviction

Health news and commentary from around the Web gathered by 番茄社区app staff

A photo of a senior woman sitting on her couch and talking on the phone.

Telehealth, Default Orders Show Promise in Palliative Care

Telecare improved quality of life for people with chronic illnesses

A photo of a senior woman laying in a hospital bed while receiving hemodialysis.

Top Insomnia Treatments Offer Little Relief for Dialysis Patients

CBT, trazodone outcomes were "surprising"

Go Vegetarian to Avoid COVID? Making Dialysis Centers Work Better

Also in TTHealthWatch: diagnostic errors among hospitalized patients

A computer rendering of a transparent body with the kidneys highlighted.

In Acute Kidney Disease, SGLT2 inhibitors Were All-Around Protective

Risk of all-cause mortality, MAKE, and MACE were significantly reduced

A photo of a salt shaker lying on its side behind a pile of salt.

For the Sake of Your Kidneys, Think Twice About Reaching for the Salt Shaker

Higher CKD risk observed among people who added salt to their food

A photo of a physician holding a urine sample container in his blue rubber gloved hand.

Should Normal Range of Albumin Be Redefined for Cardiovascular Health?

Mildly raised UACR partly mediates link between poor heart health and mortality

A photo of a female physician discussing a body mass index chart with her teen male patient.

Teens' High BMI Tied to Early Chronic Kidney Disease

"Enormous" risk increase seen in the highest BMI categories

A photo of a kidney model and urine specimen in front of an out of focus female physician talking to her pregnant patient

Kidney Disease in Pregnancy Often Overlooked for Care

These women had less nephrology care prior to end-stage disease onset

A photo of boxes of Kerendia tablets.

Quick Albuminuria Reduction Key Factor in Finerenone's Efficacy

4-month UACR reduction mediated 84% of kidney treatment effect

A computer rendering of a fetus in the womb.

Serial Amnioinfusions Helped Neonates Survive Without Kidneys

While trial proves "survival can be better than zero," long-term management remains a concern

SUO over a photo of the Omni Shoreham Hotel in Washington, DC.

'Watch and Wait' With Small Renal Masses: When and How Should Docs Intervene?

Phillip Pierorazio, MD, outlines how to be a good steward of active surveillance

A photo of a surgeon holding a kidney from a living donor prior to surgery.

Two-Week Prophylaxis May Prevent Hep C After Kidney Transplant

Direct-acting antiviral prophylaxis worked in all 10 cases in pilot trial

A micrograph and computer rendering of chronic kidney disease.

Methotrexate Tied to Greater Risks for Older Patients With CKD

FDA should consider warning labels based on study results, researchers argue

ACR over a photo of the San Diego Convention Center in San Diego, California

Novel Gout Drug Aces Mid-Stage Tests

Mechanism different from currently available therapies

AASLD over a photo of Hynes Convention Center in Boston, Massachusetts

AKI Response Tied to Improved Survival for Patients Waiting on Liver Transplant

Results highlight the importance of prompt recognition and treatment of acute kidney injury

ACR over a photo of the San Diego Convention Center in San Diego, California

B-Cell Depletion Helps Maintain Kidney Function in Lupus Nephritis

Secondary trial analysis boosts case for Gazyva

Kidney Week over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Kidney Week Roundup: Cell Therapy Cuts Immunosuppressive Drug Use Post-Transplant

Plus: bardoxolone methyl for diabetic kidney disease and spironolactone in hemodialysis patients

Kidney Week over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Novel Aldosterone Synthase Inhibitor Cuts Albuminuria in Phase II Trial

Trial tested BI 690517 with and without empagliflozin

Sparsentan Bests Irbesartan for Preserving Kidney Function in IgA Nephropathy

Proteinuria reduction and slower eGFR decline in 2-year PROTECT trial

ERA and SGLT2 Inhibitor Combo Cuts Albuminuria in Chronic Kidney Disease

But ZENITH-CKD trial had to pivot to only using low-dose zibotentan due to fluid retention

Kidney Week over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Sparsentan Failed to Preserve Kidney Function Over Time in FSGS

However, more patients on the drug achieved partial remission of proteinuria vs irbesartan

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