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ESC

Stopping Beta-Blockers Did Not Go as Planned for Long-Time Users

No benefit to beta-blocker interruption among MI survivors using them for secondary prevention

Wegovy Protects Against Deadly COVID Cases

Non-cardiovascular benefits observed in SELECT trial

No Aspirin After PCI? Extended P2Y12 Monotherapy? Trials Weigh In

Two trials read out, but generalizability is the question

Cancer Therapy's Lower-Limb Blood Clots Better Treated With Long Anticoagulation

A year of DOAC therapy did not result in significantly more bleeds in ONCO DVT trial

Novel Amyloid Drug Improves Mid-Term Outcomes in ATTR Cardiomyopathy

Pivotal trial "suggests the tantalizing possibility of genuine clinical improvement"

Compound in Beetroot Juice Fends Off Contrast-Induced AKI

"Provocative" results for inorganic nitrate pill shown in NITRATE-CIN trial

Less Atrial Pacing Doesn't Cut Afib in Sinus Node Dysfunction

Trial debunks strategy for higher-risk group

Immune Suppressant Stumbles for Acute Myocarditis in Early Data

Phase II trial might not end the story for anti-inflammatory approach, though

STEMI Complete Revascularization: No Point in Waiting

MULTISTARS AMI trial helps answer the timing question in multivessel disease treatment

Rush to DOACs Spells Trouble for Frail Warfarin Users

Lower bleeding risk of new blood thinners did not extend to this older subgroup

Ambulance Routing Might Not Matter After Cardiac Arrest

Trial in best-case scenario setting shows sending patients to specialty centers doesn't help

Pulsed Field Ablation Measures Up in Head-to-Head Trial

Novel catheters on par with thermal ablation, but do they meet the early high hopes?

Afib Ablation Exceeds Expectations in Sickest Heart Failure Patients

Death and surgeries delayed in end-stage heart failure

CRT-D Upgrade Suits Patients With Pacing-Related Heart Failure

BUDAPEST-CRT Upgrade is the first major trial on upgrade strategy

Trial: ECMO Doesn't Save Lives in Cardiogenic Shock

ECLS-SHOCK trial challenges current practice, guidelines

Complete PCI Better for Older MI Patients Too

Trial affirms advantage over culprit-lesion-only stenting in those ages 75 and up

Iron Infusions Narrowly Miss the Mark for Clinical Benefit in Heart Failure

Hard endpoints do not favor IV ferric carboxymaltose in well-powered HEART-FID

Colchicine Stumbles for Protecting the Heart From Thoracic Surgery

Trial meets only post hoc endpoints in extending protection to non-cardiac surgeries

SGLT2 Inhibitors, Rapid Titration, IV Iron Get a Boost in New European HF Guideline

Other recommendations also released for endocarditis, cardiomyopathies, ACS, and more

Wegovy Reduces Heavy Symptom Burden of Obesity-Related Heart Failure

Heart failure with preserved ejection fraction and obesity becoming more common

Subclinical Afib Caught on Cardiac Devices Might Be Better Left Alone

Trial shows no stroke reduction with DOAC at the cost of more adverse events

Full-Dose Anticoagulation Cuts VTE in Severe COVID-19

But is it worthwhile without a mortality benefit? Trials present complex picture

Milestone Reached for SGLT2 Inhibitor Aimed at Heart Attack Population

Good signals in people with large acute MIs at risk of developing heart failure

P2Y12 Inhibitors May Be the Better Option for Secondary Prevention in CAD

Meta-analysis challenges central role of aspirin, researcher says

Muscle Pain in Statin Patients Is Usually Not Caused by the Drug

A meta-analysis pointed to a low incidence of drug-related pain

Novel Factor XIa Inhibitors Show Promise for Bleeding Risk

Preventing ischemic events is a less clear benefit

Transradial Access for Heart Procedures Saves Lives in Most Definitive Study Yet

Approach beats coronary access through the thigh

Pendulum Swings Back for FFR-Guided Complete Revascularization

Modality helps avoid unnecessary intervention in heart attack patients with multivessel disease

Doubling Up on Heart Drugs May Delay Aortic Damage From Marfan Syndrome

Meta-analysis settles the confusion around angiotensin receptor blockers

Perfusion Tests Comparable as Second-Line Diagnostic for Chest Pain

Head-to-head trial finds "interchangeable" accuracy

Routine Stress Testing Didn't Offer Benefits to High-Risk Patients Post-PCI

South Korean trial showed no improvement in clinical outcomes at 2 years

High-Dose Flu Vaccine Promising for Mortality Benefits in Older Adults

Danish pilot study lays groundwork for larger trial looking for better CV outcomes

Extravascular ICD Gains Ground in Unfamiliar Territory

Inappropriate shocks among early challenges of device therapy under the sternum

Xarelto Risky in Rheumatic Heart Disease

Ischemic event prevention didn't pan out in INVICTUS trial

Finally, A Foundational Heart Failure Drug That Works Across the Spectrum of EF

SGLT2 inhibitor shines in landmark DELIVER trial

ADVOR Backs Add-On Acetazolamide for Cutting Congestion in Decompensated HF

Exclusion of patients on SGLT2 inhibitors was a major trial limitation, expert says

PCI Flops for Ischemic LV Dysfunction With Coronary Artery Disease

Randomized trial provides "definitive" evidence against revascularizing stable cases

Mass Cardiovascular Testing May Add Years for Some Men

Mixed results after the DANCAVAS program from Denmark

After Cardiac Arrest, No 'Best' Blood Pressure, Oxygen Target

BOX trial finds targets aiming to boost perfusion held no advantage

Breakfast or Bedtime BP Meds? Timing Doesn't Matter After All

TIME study supports taking antihypertensives whenever convenient

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