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ACG

JAK Inhibitor Maintenance Works in Severe Ulcerative Colitis

Treatment group achieved clinical remission, met clinical secondary endpoints

Maintenance IL-23 Blockade Yields Durable Benefit in Crohn's Disease

Over 50% of patients responding to induction risankizumab maintained clinical remission at 1 year

The Straight Poop on Who Benefited From a Squatting Stool

Assist device was helpful for a particular subgroup of patients

Weight Loss Program for GERD Relief?

In patients with BMI over 25, nearly 50% reduced use of acid blockers or stopped altogether

Two Mechanically Assisted Colonoscopy Devices Square Off

Randomized trial revealed one found more and larger adenomas

New-Onset Diabetes and Pancreas Cysts a Risky Mix

Study provides support for assessing diabetes markers in pancreatic cyst surveillance

Initial GI Symptoms Independently Tied to Poor COVID-19 Outcomes

Separate study finds diarrhea as a presenting symptom portended worse disease

Kiwifruit Better Tolerated Than Prunes or Psyllium for Chronic Constipation

Kiwi tied to fewer adverse events and greater patient satisfaction

More Data Tie Biologics to Fewer Colectomies in Ulcerative Colitis

Temporal trends analysis found reduction coincided with linear increase in prevalence of biologic medication

Anal Cancer on the Rise in U.S., Especially in Women

Whites also had a higher risk than Blacks for HPV-linked disease

Constipation in Older Adults Improved With Biofeedback

Small retrospective study extends efficacy observed in younger patients

Human Milk Sugars Quell IBS Symptoms

Bowel function, pain, bloating improved by 50% within a month with nonprescription supplement

Eosinophilic Esophagitis Responds to Steroid

Majority of previously treated patients responded to oral formulation of topical budesonide

No Benefit for High-Dose NSAID Post-ERCP

Rates of pancreatitis similar with standard and higher-dose indomethacin

Stelara a Hit in Ulcerative Colitis

Clinical remission achieved with two different doses of interleukin 12/23 blocker

Ringer's Lactate: A Hydration Option in Acute Pancreatitis?

Meta-analysis shows trend for lower mortality versus normal saline

FODMAP Diet Helps Fecal Incontinence

Two-thirds of patients reported improvements and more than one-third had complete remission

Menu Says Gluten-Free? Maybe Not

Study finds 32% of foods in restaurants labeled gluten-free had levels of at least 20 ppm

ACG: Focus on the Practical at Annual Meeting

Topics will range from gluten contamination to artificial intelligence for polyp detection

ACG Wrap-up: Fecal Transplant; Lynch Syndrome Screening; Probiotics for Pain

Additional highlights from this year's meeting

Deep Learning May Help Detect Colon Polyps

Computer-assisted model warrants further research

Antihistamine Improves Quality of Sedation During Colonoscopy

More research needed on diphenhydramine as an adjunct to sedation

Electronic Nose Promising for Barrett's Esophagus Detection

Test may facilitate surveillance for esophageal adenocarcinoma

ACG: Half of Gastro Docs Experience Burnout

Lifestyle, work-life balance most often associated with burnout

ACG Hosts Annual Meeting with World Gastroenterology Organisation

Thousands gather in Orlando for latest GI news, trends

Novel Sedation Agent for Colonoscopy Meets Phase III Endpoints

Remimazolam shows advantages over midazolam

IBS Drug Warrants Phase III Trial

Twice daily oral improves bowel movements, abdominal pain

Gastric Bypass Tied to Increased Risk for C. Diff Infection

May be result of decreased stomach acid secretion

Anti-IL-13 Shows Promise as EoE Treatment

Improvement in inflammation and other disease features in phase II trial

Case-Finding Flops in Detecting Celiac Disease

Researchers need better markers for disease risk

Cimzia in New Moms Found Safe for Nursing Babies

Only trace quantities found in breast milk

Coffee, Genetics May Block Hepatitis in Heavy Drinkers

Gene variant also shows possible liver-protective effect

Pregabalin Could Ease Pain, Some Symptoms in IBS-D

Pilot study shows positive results in some pain scores

Aprepitant Trial in Gastroparesis Misses the Primary Mark

But positive findings in secondary outcomes may save the day

Frozen or Powdered: Fecal Transplant Works in C. Diff

Donor stool need not be fresh for treating C. diff.

'Yes' to Routine Colonoscopies in IBD

Screening lowered colorectal cancer incidence and colon cancer mortality.

Colon Cancer Risk Rises After Endometrial Ca

LAS VEGAS -- A history of endometrial cancer at a younger age quadrupled the likelihood of a subsequent diagnosis of colorectal cancer, a retrospective analysis of administrative data showed.

Drug Relieves Opioid-Induced Constipation

LAS VEGAS -- An investigational opioid antagonist provided effective and durable relief from opioid-induced constipation in patients with chronic pain without interfering with analgesia, a randomized trial showed.

BP Drug Linked to Severe Diarrheal Illness

LAS VEGAS -- A patient's insightful question led to the identification of almost two dozen cases of severe enteropathy associated with use of blood pressure medication, investigators reported here.

ACG: GI Docs Should Ask About Abuse

SAN ANTONIO -- Gastroenterologists may want to be attuned to signs of possible abuse or trauma among their patients, a researcher suggested here.

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