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News, opinions and meeting coverage in hospital-based medicine.

FDA WARNING Obeticholic acid (Ocaliva) over two bottles of Ocaliva over a computer rendering of a liver with cirrhosis.

FDA Restricts Ocaliva Use in Primary Biliary Cholangitis

Liver failure, need for liver transplant reported in patients with advanced cirrhosis

The YouTube video thumbnail for this video with Dr. Zubin Damania and Marty Makary, MD and the words LEAST WRONG ABOUT COVID?

Op-Ed: Who Was Least Wrong About COVID?

ZDoggMD and Marty Makary review their pandemic hits and misses

A computer rendering of the COVID-19 virus sliced in half to show the interior

Why CDC Changed Its 'Breakthrough Case' Definition

Will new monitoring tactic miss the "full picture" of COVID infections among the vaccinated?

A man with his face in his hands sits in the center of three chairs in a waiting room

Three Reasons Your Patients Are Unhappy

How to practice on a human level

50 Hospitals Get Dubious Ranking on Racial Inclusion

"If you want an illustration of what structural racism is, this is it"

A mature Black male physician shows info on a tablet to his mature Asian female patient who is wearing a headwrap

Op-Ed: A Door Opens to Transform Cancer Care

Incoming CMS Administrator Chiquita Brooks-LaSure brings hope to the cancer community

A blue gloved hand holds a test tube of blood labeled Testosterone - Test over a form with results showing low testosterone.

Low Testosterone Could Be Bad News in COVID-19

In small study, men with low levels were more likely to have severe illness

Breast Cancer Screening During COVID Reveals Inequities

Vinay Prasad, MD, MPH, discusses new findings and his takeaway

A sad little boy with his face to a wall

Op-Ed: Love Can Conquer Trauma

My wife helped me heal old mental wounds

A baby cries over the shoulder of his mother who is talking to an out of focus female physician

Neonatal Seizures: When Should Treatment Stop?

Study follows infants with acute seizures to track neurodevelopment

Microbiome Therapies for Recurrent C. Diff Advance

Clinical trial success for two proprietary bacteria mixtures

A male physcian at the bedside of his male patient uses virtual reality to look at MRI images of his brain.

Evaluating Tech for Clinical Use

What factors should you consider?

A stern looking mature male physician making the stop gesture with his right hand

Op-Ed: Down With the Gatekeepers of Medicine

Educators should be mentors, rather than weeding out those they deem unfit

A computer rendering of the acute pancreatitis

These Risk Factors Can Make Severe Pancreatitis Worse

Not surprisingly, clinical outcomes also suffered

A graphic of a petition which reads: STOP TOKYO OLYMPICS TO SAVE OUR LIVES

Op-Ed: Let the Olympic Games Be Canceled

Amid continued crisis, now is not the time for celebrating athletic achievement

A graphic from the NNU which reads: Nurses Say >> CDC MUST REVOKE Dangerous Mask Guidelines

Nurses Union Blasts 'Dangerous' CDC Mask Guidance

NNU charges CDC used unreliable data and disregarded variant threat, low vaccination rates

A photo of an astronaut during a spacewalk outside of the International Space Station.

After 6 Months in Space, Eyes and Brain Show Changes

But it's likely these alterations are uncoupled from each other

ATS over a computer rendering of alveoli

Poorly Controlled Sleep Apnea Tied to More COVID-19 Infections

As adherence to PAP increased, infection rates fell, researcher says

A YouTube video thumbnail with Rohin Francis, MBBS, Jimmy Kimmel and the words: The Patient IS NOT THE PUNCHLINE

Op-Ed: How Not to Message the Public on COVID Vaccines

A "cringe-inducing" public service announcement with doctors and nurses

ATS over a computer rendering of alveoli

CPAP May Cut Cardiac Events in Some At-Risk Apnea Patients

Greater pulse rate response tied to greater calculated treatment benefit of CPAP

A photo of a woman cupping her ear next to an audio-off icon.

Sudden Hearing Loss Reported After COVID Vaccines

Preliminary report teases apart VAERS data to identify most likely cases

A pale mature woman wearing a head wrap and sitting in a wheelchair pets her service dog

Breast Cancer and MS: New Data Shed Light on Survival

Study compares breast cancer patients with and without MS

A photo of Amani Jambhekar, MD, MBA

Op-Ed: 'Yes, I Am the Surgeon,' She Said

Growing recognition of women as surgeons starts with changes in healthcare systems

A Stelara auto injector needle over a grid of close up psoriasis images.

For Safety, One Biologic a Winner in Psoriasis, Psoriatic Arthritis

Lower hospitalization rates compared with other biologics or small molecule therapies

ACC over a computer rendering of the human heart and major blood vessels

Xarelto Flops for COVID-19 Clot Prevention Outside ICU

ACTION trial adds nuance to the story from large platform trials

A stressed looking female physician with her hand on her forehead leans against a wall and looks at papers on a clipboard

Op-Ed: This Doc Has 'Post-Litigation Stress Disorder'

The legal system versus the doctor-patient relationship

A photo of Elon Musk next to a photo of Mars

Elon Musk's Asperger's Syndrome

Tesla and SpaceX founder opens up on national TV

A photo of Robert Pearl, MD and the cover of his book Uncaring

The Problem With Prestige

An excerpt from "Uncaring: How the Culture of Medicine Kills Doctors and Patients"

ATS over a computer rendering of alveoli

Antibody Cocktail Reduced Poor Outcomes in High-Risk COVID

Casirivimab plus imdevimab showed clinical efficacy in phase III trial

ATS over a computer rendering of alveoli

Dupixent Improves Lung Function in Kids With Uncontrolled Asthma

VOYAGE phase III trial also showed exacerbation reductions

A male physician speaks into a microphone held by a news reporter

Op-Ed: Will the Real COVID Experts Please Stand Up?

A core set of principles separate those who make good and bad policy decisions

ACC over a computer rendering of the human heart and major blood vessels.

Novel Heart Failure Agent Works Best in Sickest Patients

Omecamtiv mecarbil provides benefit to those with low LVEF

ACC over a computer rendering of the human heart and major blood vessels.

Plavix Beats Aspirin, Brilinta After Stenting

HOST-EXAM and TALOS-AMI studies from South Korea focus on aspects of DAPT

ACC over a computer rendering of the human heart and major blood vessels.

Finerenone May Delay AFib Onset in Patients With CKD and Diabetes

Risk of kidney or CV events reduced regardless of atrial fibrillation or atrial flutter history

ATS over a computer rendering of alveoli

COVID Patient 'Lottery' Ensured Scarce Drugs Divided Equitably

System prioritized, deprioritized certain patient groups

Electrocardiogram on top and bottom of image with CardioBreak in the center.

Pacemaker Interference Warning; Religious Fasting and CVD; Toothpick in the Heart

Recent developments of interest in cardiovascular medicine

ACC over a computer rendering of the human heart and major blood vessels.

Personalized Rehab Helpful in Heart Failure Patients

Trial showed improvements in physical functioning and quality of life compared with usual care

ACC over a computer rendering of the human heart and major blood vessels

LAA Occlusion During Surgery Cuts Stroke Risk

Afib patients on antithrombotic therapy saw gains from add-on left atrial appendage occlusion

A wizened female physician leans against a window in the sunlight

The Life Cycle of Emotion in Medicine

Perspectives change throughout a career

A photo of the exterior of Indiana University Health hospital next to a selfie Susan Moore took from her hospital bed.

Review ID's Racism During Care of Black Doctor Who Died of COVID

"Lack of empathy, compassion, and awareness of implicit racial bias," external review concludes

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