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News, opinions and meeting coverage in oncology/hematology.

A view of the tribute in light in Manhattan during the anniversary of 9/11.

Cough, Cancer, PTSD: Two Decades of World Trade Center Studies

Research has revealed the fallout of response to a crisis

FDA ADCOMM AAV Gene Therapies over a computer rendering of the liver anatomy.

Liver Toxicity in Gene Therapy Trials Could Merit Stricter Entry Criteria

FDA panel weighs in on lower vector doses and role of animal studies

An image of of package of Xeljanz

FDA Slaps Restrictions on JAK Inhibitors Over Serious Safety Risks

Use for inflammatory conditions limited to those who fail on TNF blockers

A computer rendering of testicular cancer.

Study Confirms, Clarifies Excess Mortality in Testicular Cancer Survivors

Platinum-based chemotherapy, RT increased mortality risk of second cancers, other causes

FDA APPROVED over a computer rendering of a tumor.

FDA Grants Tissue-Agnostic Approval to Dostarlimab for dMMR Tumors

Overall response rate of 41.6% in various tumor types with mismatch repair deficiency

A photo of radiotherapy equipment

Medicare's Radiation Oncology Payment Model Vexes Oncology Community

Participation required for certain radiation oncology practices starting next January

A patient鈥檚 eye view of a surgeon in the operating room holding a $1 bill in tweezers.

Higher Prices, No Difference in Resource Use at NCI Cancer Centers

Negotiated facility prices, not surgeon costs, appeared to drive the differences

A close up of a woman in a hospital lowering her waistband to reveal a medical dressing over a hysterectomy scar.

Improved Survival in Metastatic Uterine Cancer With Hysterectomy Plus Chemo

Data extend surgery's advantage from locally advanced to distant metastases

A computer rendering of t-cells attacking a COVID-19 virus.

Call in the T-Cell Cavalry to Fight COVID in the Immunocompromised

Preliminary research suggests immunotherapy could play role in protecting vaccine non-responders

An MRI image of angiomyolipomas of both kidneys.

More Data Support Active Surveillance for Small Renal Masses

Most patients avoided surgery with no metastasis, better focus on aggressive disease

Photo of vials of the drug Shingrix.

Shingrix OK'd for Immunocompromised Adults

CDC's vaccine committee currently discussing vaccine for this population, manufacturer says

A young woman reacts with shock and dismay at what she鈥檚 seeing on her laptop.

A Patient Care App Diagnosed Me With Cancer

No one should receive a serious diagnosis this way -- not even a doctor like myself

Glasses of various alcoholic beverages including beer, wine, a mojito, whiskey on the rocks, a shot, and a cocktail.

Raise a Glass? Study Tallies Cancer Cases From Booze

Heavy drinking habits accounted for about half of new alcohol-associated cases

An abstract illustration of two people hugging.

Empathy: The Most Critical Skill in Medicine

Caring for a patient means putting yourself in their shoes

ESMO GI over a computer rendering of an endoscope illuminating a tumor in a stomach

Response Soars With Anti-PD-1 Drug for HER2-Positive Stomach Cancer

Almost 50% relative increase in ORR with pembrolizumab plus trastuzumab and chemotherapy

ESMO GI over a computer rendering of an endoscope illuminating a tumor in a stomach

PD-1 Inhibitor Boosts Survival in Treated Esophageal Cancer

Benefit with China-developed tislelizumab in all patients and EU-North American subgroup

CT imaging of primary ameloblastoma with measurement and three-dimensional reconstruction.

Woman Loses 6-Year Battle With Mouth Tumor

Rare ameloblastoma rapidly recurs and metastasizes despite numerous radical excisions

ESHRE over a microscope image of embryo selection for in vitro fertilization

IVF Babies at No Increased Risk of Childhood Cancers

No associations seen with intracytoplasmic sperm injection or frozen embryo transfer, study found

A coal waste pile West of Trevorton, Pennsylvania.

House Members Argue for Puerto Rico Coal Plant Shutdown

Plant is releasing toxic coal ash, sickening the nearby community, lawmakers and witnesses say

ESMO GI over a computer rendering of an endoscope illuminating a tumor in a stomach

'Clinically Meaningful' Survival Gain in Neuroendocrine Tumors

Near 1-year improvement with radionuclide agent misses statistical significance

ESMO GI over a computer rendering of an endoscope illuminating a tumor in a stomach

Adjuvant Combo Boosts Survival in Resected Pancreatic Cancer

Four-month gain in OS with the addition of nab-paclitaxel to gemcitabine

Do 'Robots' Offer Any Clear Surgical Advantage?

Review says no, and Vinay Prasad believes it's a sobering reflection on medical technology

EASL over a computer rendering of a liver

Adding PD-1 Inhibitor Shows Promise in Potentially Resectable HCC

"Safe and successful conversion therapy" with hepatic arterial infusion chemo plus sintilimab

FDA ODAC over a PET scan of squamous carcinoma of the anal canal

Hold Off on Approving Anal Cancer Drug, Advisors Tell FDA

ODAC recommends deferring approval of new PD-1 inhibitor until confirmatory trial results are in

Cancer cells with OncoBreak in the center.

Start Thinking 'Cure'; One More Hug; Mortgages and Breast Cancer Survival

News, features, and commentary about cancer-related issues

An FDA APPROVED seal over a photo of prescription bottles on a shelf

The FDA Is Failing the American People

The agency's recent decision to approve aducanumab offers more evidence of a broken system

Cancer cells with OncoBreak in the center.

COVID Vaccine Protection; 'Until You Die From the Cancer'; What's Palliative Care?

News, features, and commentary about cancer-related issues

ASCO over a computer rendering of a cancer cell and lymphocytes

Bispecific Antibody Active in NRG1-Positive Pancreatic Cancer

Zenocutuzumab turns in promising results in early-phase trial involving multiple solid tumors

ASCO over a computer rendering of a cancer cell and lymphocytes

Promising Early Data for Bladder-Sparing Cancer Treatment

Bladder-intact DFS at 1 year nears 90% for muscle-invasive bladder cancer

ASCO over a computer rendering of a cancer cell and lymphocytes

Perioperative Chemo Enough in Esophageal Cancer?

MAGIC/FLOT regimens yielded similar overall survival to multimodal CROSS regimen

ASCO over a computer rendering of a cancer cell and lymphocytes

Small PFS Bump in Synovial Sarcoma With Novel Drug

But questions raised over control arm and whether improvement represents a meaningful benefit

ASCO over a computer rendering of a cancer cell and lymphocytes

PD-1 Inhibitor Shows Benefit in Nasopharyngeal Cancer

Toripalimab plus first-line chemo improved survival in recurrent/metastatic disease

ASCO over a computer rendering of a cancer cell and lymphocytes

Survival Boost With First-Line Immunotherapy for Esophageal Cancer

Nivolumab plus ipilimumab or chemo offers new option for advanced, metastatic disease

A close up of an IV drip next to a vial of Keytruda (pembrolizumab) with an out of focus senior man in the background

First-Line Chemo Plus Immunotherapy Falls Short in Bladder Cancer

Adding pembrolizumab to cisplatin-based chemotherapy did not improve survival outcomes

A man wearing an immobilization mask undergoes radiotherapy for head and neck cancer.

Radiation Speeds Up Biological Aging in Head and Neck Cancer

Epigenetic age acceleration linked with greater inflammation and fatigue

A vial of Avastin (bevacizumab) over an MRI scan of a tumor in the bladder

Bevacizumab Misses Mark in Untreated Metastatic Bladder Cancer

No improvement in overall survival when added to cisplatin-containing chemotherapy

FDA ADCOMM Teplizumab over a computer rendering of antibodies

Drug to Delay T1D Gets Tepid Endorsement by FDA Advisors

Feelings mixed on safety and efficacy evidence for novel biologic

A female nurse tends to her senior female patient who is home from the hospital

Hospital at Home May Reduce Hospitalization, Costs for Cancer Patients

Study demonstrated efficacy, cost-effectiveness of providing hospital-level services at home

A computer rendering of lymph nodes over a whole body PET/CT scan

Lymph Node Findings on PET: Cancer or COVID Vaccine?

Post-jab radiotracer uptake "could prompt unnecessary biopsies and treatments"

A computer rendering of a gastric ulcer

Potassium Acid Blocker No Better Than PPI for Artificial Gastric Ulcers

Small Japanese trial found similar outcomes with both drugs

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