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Lymphoma

News, opinions and meeting coverage in oncology/hematology.

A photo of a male technician using a light microscope to inject a sperm into an egg.

IVF Helps Patients Trying to Build Families. An Alabama Court Put That in Doubt

"Every month that you're not pregnant feels like grief"

A photo of families holding handwritten signs at a protest outside a sterilization plant in Illinois.

Toxic Gas That Sterilizes Medical Devices Prompts Safety Rule Update

The EPA is set to take action after public outcry

A computer rendering of several sperm swimming towards one side of an egg and very few swimming towards the other side.

Male Fertility Problems in the Family Linked to Cancer Risk

Low sperm levels were tied to specific cancers in family members

A scanning electron microscope image of a cell heavily infected with SARS-CoV-2 virus particles

Most Immunocompromised Patients Clear Omicron Infections

B-cell malignancies, B-cell treatments associated with longer duration of infection

A photo of stacked creosote soaked timber next to a railroad track.

How Can Cancer Risk Be Cut in Communities Exposed to Toxins?

Group outlines plan to bring the latest testing and treatment to medically underserved minorities

A computer rendering of CAR-T immunotherapy.

CAR-T Investigation: FDA Leaders Detail Decision on Cancer Risk Warning

Post-treatment cases grow to 22 since products' initial approvals

A computer rendering of CAR T cells and a cancer cell.

FDA Calls for New Boxed Warning on All CAR-T Products

Most serious warning would alert patients, providers on potential risk for secondary malignancies

Onco Break over a computer rendering of a cancer cell.

Two Million Cancers; Casgevy OK'd for Thalassemia; Rectal Exams and Prostate Cancer

News, features, and commentary about cancer-related issues

Pirtobrutinib Shows Potential in Heavily Pretreated Follicular Lymphoma

"Safety profile is one of the real advantages" of non-covalent BTK inhibitor, says panelist

Novel Combination Active in Large B-Cell Lymphoma, Even After CAR-T

But where mosunetuzumab/polatuzumab vedotin would fit among available options remains a question

A photo of the packaging and blisterpack of Carvedilol tablets

Carvedilol No Help in Preventing Heart Failure in Childhood Cancer Survivors

While safe, the results do not support use of the drug in anthracycline-exposed survivors

Axi-Cel Shows Durable Responses, Prolongs Overall Survival in Older LBCL Patients

Our panel discusses findings from the ZUMA-12 study and the ZUMA-7 study

Liso-Cel a Potential New CAR-T Option for High-Risk R/R Follicular Lymphoma

Study results show impressive efficacy, favorable safety profile in the second line

Chemo-Free Quadruplet Promising as Initial Treatment in DLBCL

Approach could allow for a response-adapted reduction of CHOP

Tisa-Cel Yields Durable Responses in R/R Follicular Lymphoma

Our panel of experts discuss 3-year findings from the phase II ELARA study

Responses to Mosunetuzumab in Follicular Lymphoma Remain Durable at 3 Years

Bispecific antibody also shows high response rates in frontline setting

Positive Results for Odronextamab in Relapsed/Refractory DLBCL

But experts aren't sure where it would fit in with currently approved bispecifics

A computer rendering of lymphoma cells in the blood

JAK1 Inhibitor Shows 'Remarkable' Activity in T-Cell Lymphoma

Phase II findings on golidocitinib will form the basis of an accelerated approval application

ASH over a photo of San Diego Convention Center.

Ibrutinib-Venetoclax Improves PFS in R/R Mantle Cell Lymphoma

Will results revive ibrutinib role in MCL following withdrawal of accelerated approval?

ASH over a photo of San Diego Convention Center.

ASCT Tops CAR T-Cell Therapy for Relapsed LBCL in Complete Remission

Better 2-year PFS, OS, but not applicable to primary refractory disease

A computer rendering of non-Hodgkin lymphoma cells in the blood flow

Rituximab Maintenance Boosts Survival for Older Adults With MRD-Negative MCL

Patients with treatment-sensitive disease may benefit most from continued treatment, says expert

A photo of a young female physician looking at MRI scans of her patient鈥檚 brain.

Charting the Course: From Young Adult Leukemia Patient to Oncologist

My experience shaped how I care for patients today

YIR FOLLICULAR LYMPHOMA over a microscope image of follicular lymphoma.

Year in Review: Follicular Lymphoma

A promising year for bispecific antibodies

A scanning electron microscope image of CAR-T cells attacking a cancer cell.

FDA Investigating 'Serious Risk' of Malignancy After CAR-T Therapy

Applies to all approved therapies, but benefits still outweigh risks, agency says

A photo of a spilled bottle of Eliquis tablets.

Apixaban Prophylaxis Fails to Reduce Clots in Pediatric ALL

However, it may benefit children at increased risk of thrombosis

FDA ADCOMM pralatrexate (Folotyn), belinostat (Beleodaq) over a computer rendering of lymphoma cells in the blood flow.

FDA Panel: Tolerating Approval Outliers Would Set 'Dangerous Precedent'

No easy answers for two drugs for rare lymphoma on long cruise with accelerated approval

A photo of the vial and packaging of Aliqopa.

Lymphoma Drug Copanlisib to Be Pulled From U.S. Market

Failed confirmatory trial takes down another PI3K inhibitor

Onco Break over a computer rendering of a cancer cell.

Vitamin D for Neuropathy; Good & Bad News for CAR-T; New Labeling for Surgical Mesh

News, features, and commentary about cancer-related issues

Onco Break over a computer rendering of a cancer cell.

Cancer Drug Shortages for Kids; Pharma Agrees to Price Talks; Catch-Up on Screening

News, features, and commentary about cancer-related issues

A photo of a surgeon performing radiofrequency ablation

Weight-Loss Surgery Tied to Lower Blood Cancer Risk in Women

Consider surgery for primary prevention in people with obesity, researchers suggest

SOHO over a photo of George R. Brown Convention Center in Houston, Texas.

High Rate of Durable Responses in R/R Lymphoma With Bispecific Antibody

Response rate exceeds 60%, with 15- to 20-month duration with epcoritamab

SOHO meeting

Study Questions Value of Interim PET Imaging to Guide Frontline Hodgkin Treatment

One of 40 patients changed treatment but all remained on brentuximab regardless of scan results

A close up photo of a nurse taping the intravenous line to her male patient鈥檚 wrist during chemotherapy.

Standard Lymphoma Therapies Tied to Higher Risk for New Malignancies

Increased risk for non-melanoma skin cancer, MDS, AML versus the general population

A photo of a female nurse prepping her senior male patient for chemotherapy.

Adcetris Plus Chemo Effective in HIV-Related Hodgkin Lymphoma

Researchers call study "practice changing," although outside experts urge caution

A photo of a vial of Keytruda over a high magnification micrograph of primary mediastinal large B-cell lymphoma

Anti-PD-1 Alone Produces Durable Responses in Relapsed/Refractory PMBCL

More than 80% of responding patients remained in response at 4 years

A photo of bottles of Jaypirca 100 mg and 50 mg.

Non-Covalent BTK Inhibitor Yields High Response Rate in Pretreated CLL

73% of patients with prior exposure to covalent BTK inhibitors responded

Onco Break over a computer rendering of a cancer cell.

WHO Links Sweetener to Cancer; Younger-Age CRC Risk; PCOS and Ovarian Cancer

News, features, and commentary about cancer-related issues

A photo of a man鈥檚 torso affected by erythroderma.

Why Did Older Man Develop Itchy, Full-Body Rash?

Here's how the medical team diagnosed and treated the rare inflammatory skin disorder

FDA APPROVED glofitamab (Columvi) over a computer rendering of antibodies attacking cancer cells.

New Bispecific Antibody Approved for Tough-to-Treat Lymphoma

Approval of glofitamab was based on a phase I/II study that showed a 56% overall response rate

Onco Break over a computer rendering of a cancer cell.

Pushback on Price Negotiation; Genetic Testing Lags; More Foreign Help for Shortages

News, features, and commentary about cancer-related issues

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