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News, opinions and meeting coverage in oncology/hematology.

Onco Break over a computer rendering of a cancer cell.

Ancient DNA May Fuel Cancer; ASCO Appeals to Oncologists; Pesticide Cancer Risk

News, features, and commentary about cancer-related issues

A photo of an Olympic venue in Paris decorated for the 2024 Summer Olympics.

These Athletes Weren't Doping. Their Genes Made It Look Like They Did.

Advanced sequencing revealed genetic reasons for high hemoglobin, hematocrit levels

A photo of a smiling woman holding a positive pregnancy test.

'Realistic Chance for Pregnancy' After Stem Cell Transplant, German Study Suggests

77% of pregnancies resulted in live births

Onco Break over a computer rendering of a cancer cell.

Top Cancer Centers; Phase III Win in Prostate Cancer; Screening Recs for Anal Cancer

News, features, and commentary about cancer-related issues

A computer rendering of blood escaping from a broken vessel.

Efanesoctocog Alfa Prevented Bleeding in Kids With Severe Hemophilia A

No factor VIII inhibitors developed among the 74 boys included in the study

Onco Break over a computer rendering of a cancer cell.

A First in Total Larynx Transplant; 'Sniffing' Out Lung Cancer; Gen X Cancer Toll

News, features, and commentary about cancer-related issues

A computer rendering of multiple myeloma cells.

Refractory Multiple Myeloma Responsive to Immunotherapy Plus Low-Dose Radiotherapy

A third of patients who had received multiple prior lines of therapy responded, small study shows

Belantamab Mafodotin: The Comeback Drug in Multiple Myeloma

Joseph Mikhael, MD, leads a discussion on the DREAMM-7 and DREAMM-8 trials

Onco Break over a computer rendering of a cancer cell.

Unexplained CAR-T Death; Americans Spurn Sunscreen; Improving Diversity in Trials

News, features, and commentary about cancer-related issues

A photo of a female teen wearing a head scarf being comforted by her mother.

Young Cervical Cancer, Leukemia Survivors at Greater Risk of Obstetric Complications

Population-based study suggests reassurance for most, high-risk strategies for some

FDA APPROVED crovalimab (Piasky) over a computer rendering of blood flowing inside a vessel.

Subcutaneous C5 Inhibitor Approved for PNH

Longer-acting crovalimab designed for more sustained effect and less treatment burden

Onco Break over a computer rendering of a cancer cell.

EU Adds CAR-T Warning; New Blincyto Indication; Good News in Pancreatic Cancer

News, features, and commentary about cancer-related issues

EHA over a photo of IFEMA Madrid in Spain.

Glofitamab Regimen Improves Survival in DLBCL

Granted accelerated approval last year, bispecific antibody passes its confirmatory test

Using MRD Status to Deescalate Multiple Myeloma Therapy

Joseph Mikhael, MD, leads a discussion on the findings of the MRD2STOP study

A computer rendering of diffuse large B-cell lymphoma cells.

Multidrug Regimen Could Change Treatment Landscape for Relapsed/Refractory DLBCL

High-rate of durable responses with ViPOR sparks talk of supplanting CAR-T in second line

A computer rendering of monoclonal antibodies.

Novel Anti-CD38 Drug Shows Promise for Immune Thrombocytopenia

"Rapid and sustained" efficacy in 95% of pretreated patients in small trial

EHA over a photo of IFEMA Madrid in Spain.

Three-Drug Regimens Make Case for a Role in Untreated and Relapsed/Refractory CLL

Undetectable MRD rates of 90% or higher, PFS of 7 years or more

EHA over a photo of IFEMA Madrid in Spain.

New Standard of Care in High-Risk Acute Promyelocytic Leukemia?

All-trans retinoic acid plus arsenic trioxide and idarubicin improved EFS over standard

EHA over a photo of IFEMA Madrid in Spain.

Atezolizumab Consolidation Impresses in High-Risk DLBCL

Will 2-year DFS of 88%, OS of 96% renew interest in checkpoint inhibitor consolidation?

Adding Isatuximab to Standard Backbone Prolongs PFS in Myeloma

Joseph Mikhael, MD, leads a roundtable discussion on two positive phase III trials from ASCO

Onco Break over a computer rendering of a cancer cell.

Upping Immunotherapy Activity; A Win for Lung Screening; Looming Drug Price Break?

News, features, and commentary about cancer-related issues

A computer rendering of CAR T cell therapy in Diffuse large B-cell lymphoma

New Clues to Origin of T-Cell Lymphoma After CAR-T Therapy

Co-mutations, viral link, potential common susceptibility emerge from two studies

A photo of Alunbrig (brigatinib) tablets.

Brigatinib Makes Its Case for ALK-Positive ALCL in Small Study

Second-gen ALK inhibitor induces high response rate, associated with impressive survival

FDA APPROVED imetelstat (Rytelo) over a photo of a bag of blood in blue rubber gloved hands.

Telomerase Inhibitor Approved for MDS-Related Anemia

Imetelstat indicated for lower-risk myelodysplastic syndromes with transfusion-dependent anemia

A photo of a female radiologist readying her male patient for radiotherapy.

Near-Perfect Control of Slow-Growing Lymphoma With Low-Dose Radiotherapy

All but four of 24 patients had complete responses to 4 Gy, local control rate of 96% at 3 years

Onco Break over a computer rendering of a cancer cell.

'Unusual' Cancers After Pandemic; A Win in TNBC; Shortage Pauses Clinical Trial

News, features, and commentary about cancer-related issues

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Star Singer's Illness; AI Imitating the Dead; Internet-Addicted Brains

Health news and commentary gathered by 番茄社区app staff

ASCO over a photo of McCormick Place in Chicago, IL

Triplet Notches Survival Win in Heavily Pretreated DLBCL

Benefit with BV plus lenalidomide-rituximab seen in those who relapsed after CAR-T or transplant

ASCO over a photo of McCormick Place in Chicago, IL

Blenrep-Based Regimen Yields PFS Benefit in Relapsed/Refractory Myeloma

Second belantamab mafodotin-containing triplet to show potency in this setting

ASCO over a photo of McCormick Place in Chicago, IL

Kinder, Gentler Regimen for Classical Hodgkin Prevails in Randomized Trial

Better efficacy with brentuximab vedotin versus standard chemo, substantially less toxicity

Onco Break over a computer rendering of a cancer cell.

Fewer Suicides in Cancer Patients; Circadian Rhythm Boost; HIV Vaccine for Cancer?

News, features, and commentary about cancer-related issues

ASCO over a photo of McCormick Place, in Chicago, IL

STAMP Inhibitor Tops Imatinib, Second-Gen TKIs for Newly Diagnosed CML

The benefit-risk profile could change the treatment paradigm in CML, expert says

A photo of a male artist tattooing his male client in a parlor in Stockholm, Sweden.

Tattoos May Be a Risk Factor for Lymphoma

Swedish study suggests a 21% higher risk for lymphoma in those with tattoos

The YouTube thumbnail for this video with a cartoon nurse and the words: MOST BURNT OUT SPECIALTY

Five Doctor 番茄社区app With the Most Burnout in 2024

Emergency medicine and ob/gyn top the list

A computer rendering of antibodies in the blood.

Doubt Cast on MGUS-Autoimmune Disease Link

Population-based study fails to confirm earlier findings

A photo of infected blood victim Brendan West.

What to Know About the U.K.'s Tainted Blood Scandal

Tens of thousands contracted HIV or hepatitis from transfusions during the 1970s and 1980s

Mortality in U.S. Youth; Gene Therapy for Sickle Cell Disease

Also in TTHealthWatch: updated breast cancer screening guidelines

Onco Break over a computer rendering of a cancer cell.

Cancer Vaccines' Emergence; More Focus on Side Effects; A Nudge for Exercise

News, features, and commentary about cancer-related issues

A computer rendering of acute myeloid leukemia cells in the blood.

Venetoclax Combo Safe, Effective in AML Patients Age 80 and Up, Real-World Data Show

Study finds survival is comparable to that seen in younger patients in VIALE-A trial

A photo of a box of Adzynma

Impact of Recombinant Replacement Therapy Detailed in Genetic Clotting Disorder

Trial that led to FDA approval shows a big difference in replacement levels versus usual care

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