Anti-CDK4/6 Fails to Top Chemo in HR-Positive MBC Similar PFS with chemo, palbociclib plus exemestane or fulvestrant after progression on aromatase inhibitor Dec 13, 2019
Checkpoints Show Different Outcomes in Breast Cancer Atezolizumab misses complete response benefit in triple negative patients Dec 13, 2019
T-DM1 Falls Short as Less-Toxic Option for Early Breast Cancer Promising efficacy but higher discontinuation rates and cost likely a deterrent Dec 13, 2019
Edging Closer to OS Benefit With Novel Anti-HER2 Drug Larger benefit with margetuximab in most common HER2 breast cancer phenotype Dec 12, 2019
New Standard for Metastatic HER2 Breast Cancer Consistent PFS, OS benefit with combination including oral HER2 inhibitor tucatinib Dec 11, 2019
Survival Bump With Oral AML Maintenance Ten-month OS gain, doubling of RFS with oral azacitidine in transplant-ineligible patients Dec 10, 2019
Docetaxel First May Boost Survival in mCRPC Superior outcomes observed versus approach where chemo follows newer agents Dec 05, 2019
IGHV-Unmutated CLL: Gene Signature May Predict Outcomes After First-Line FCR Prognostic tool may predict who is likely to achieve a relatively long remission Oct 15, 2019
FCR Still an Option in IGHV-Unmutated CLL? Gene signature identifies lower-risk group with greater chemoimmunotherapy benefit Oct 08, 2019
Novel CDK 4/6 Inhibitor Fails in Triple Negative Breast Cancer Misses primary endpoints but has unexpected key benefit Oct 01, 2019
Ibrutinib's Cardiotoxicity Comes Into Focus Study identifies new cardiac events linked to so-called targeted therapy Sep 25, 2019
Tx Deintensification Wins in Head and Neck Cancer, But ... Only against another less-intensive approach in HPV-positive disease Sep 18, 2019
'Dirtier' Drugs Step Aside in RET-Positive NSCLC Over two-thirds of patients respond to selective RET inhibitor Sep 09, 2019
Depth of Tumor Response a Better Survival Predictor Could improve on RECIST as outcome measure in oncology Jun 05, 2019
Omitting Chemo Feasible in First-Line HER2+ Breast Cancer? De-escalation showed mixed results in metastatic disease May 01, 2019
'Magic Mouthwash' Little Help for Radiation-Induced Mucositis Only statistical improvements in pain scores for head and neck cancer patients Apr 16, 2019
Rheumatologist's Primer on Checkpoint Inhibitors Specialist reviews the landscape of cancer drugs' autoimmune side effects Apr 09, 2019
PARP Inhibitor Maintenance for Pancreatic Cancer Study takes cue from new treatment paradigm in BRCA-mutant ovarian cancer Apr 03, 2019
Reversing Melanoma Resistance to Immunotherapy HDAC inhibitor/anti-PD-1 combo active after initial anti-PD-1 failure Apr 02, 2019 video
MET Inhibitor Rescues Some Targeted Tx Failures in NSCLC Savolitinib promising in patients with MET-based resistance to EGFR inhibition Apr 01, 2019 video
Aggressive Tx Remains Common for Adults, Children Near Death Many patients continue with treatments they probably don't need Mar 30, 2019
Early Data Send Strong Signal in Advanced Gyn Cancers Clinical benefit rate tops 90% in pair of single-center studies Mar 19, 2019
When PARP Inhibitors Fail in Ovarian Cancer Study identifies subgroup for whom another go could be worthwhile Mar 18, 2019
Avelumab Combo Falls Short in Advanced Ovarian Ca But showed promise in PD-L1-positive group Mar 18, 2019
Zytiga May Up Mortality Risk in Prostate Cancer Patients With CVD Increased hospitalizations seen among all abiraterone-treated patients Feb 27, 2019
Genetic Profiling Disappoints for CUP Survival But testing in cancer of unknown primary site did help with prognosis Jan 24, 2019
Surgery/HIPEC Safer Than Other High-Risk Cancer Procedures Lower infection, 30-day mortality rates than with Whipple, esophagectomy Jan 15, 2019
Cancer Treatment and Arthritis: A Growing Complaint Will checkpoint inhibitor-related arthritis outstrip RA in frequency? Dec 27, 2018
Higher Risk of Shingles Seen in Patients With Certain Cancers Vaccine development may help with prevention of herpes zoster in this population Dec 14, 2018
Visual Guide to AVERT's VTE Prevention in Cancer Apixaban effective against important chemotherapy side effect Dec 07, 2018
Low-Dose Tamoxifen Feasible Option in Breast Cancer Women appear to prevent recurrence in early stage cancers with 5 mg dosing Dec 06, 2018
Cetuximab Fails Twice vs Cisplatin for HPV-Related Oral Ca Cetuximab resulted in more patient deaths across U.S., German studies Oct 23, 2018
Study: Paclitaxel Best for HIV-Related Kaposi's Sarcoma Other chemotherapies fall behind in resource-limited setting Jul 29, 2018
Is Drug Vial Optimization in Peril? Pharmacy Practice News Also, how to advance your leadership skills Jun 20, 2018
Ditching Chemo Appears Viable in Frontline Follicular Lymphoma PFS 'nearly identical' at 3 years with novel immunomodulatory combination Jun 06, 2018
PFS Rises in Ovarian Ca with Repeat Bevacizumab Magnitude of benefit similar to first-line therapy Jun 06, 2018
Many with Metastatic Kidney Cancer Can Skip Surgery Overall survival with single-agent sunitinib better than with resection Jun 04, 2018
Hot Chemo Fails in Rare Cancer HIPEC and surgery equals surgery alone in peritoneal carcinomatosis Jun 04, 2018 video
Rare Childhood Cancer Gets First Tx Advance in 30 Years But impact unclear for U.S. rhabdomyosarcoma patients Jun 04, 2018
