Cancer and COVID; Booze and Cancer; 'Screech' Starts Chemo News, features, and commentary about cancer-related issues Jan 21, 2021
Oncotype DX Misses on Breast Cancer Risk in Black Women Accuracy of 21-gene recurrence score worse compared with white women Jan 21, 2021
Not Just BRCA: Large Studies ID Other Key Breast Cancer Risk Genes Implications for screening and other risk-management strategies, researchers say Jan 20, 2021
Most Women Satisfied With 'Going Flat' After Mastectomy Lack of surgeon support key factor in later dissatisfaction, study shows Jan 08, 2021
PARP Inhibitors Linked With Blood Cancer Risk Incidence of MDS/AML under 1%, but further investigation warranted as indications broaden Dec 28, 2020
Add-On HDAC Inhibitor No Help in Breast Cancer PFS, OS similar to endocrine therapy alone for advanced HR+ disease Dec 15, 2020
Broader Role for PARP Inhibitors in Breast Cancer? Responses in tumors with somatic or germline mutations related to HRD Dec 14, 2020
Online Tool Refines Individual Risks in Breast Cancer RSClin incorporates 21-gene recurrence score with tumor grade, size, and more Dec 13, 2020
Doctor-Patient Discord in Reporting Radiation Toxicity Physicians underrecognized substantial symptoms in more than half of patients Dec 11, 2020
Adjuvant Palbociclib Fails in Early, High-Risk Breast Cancer No iDFS benefit with 1 year of CDK4/6 inhibition following neoadjuvant chemotherapy Dec 10, 2020
Chemotherapy Improved TNBC Survival in Older Women Benefits noted in both node-negative and -positive disease, as well as for those with a comorbidity score greater than 0 Dec 08, 2020
Study Reassures on MS Patients' Breast, Colorectal Cancer Risk But higher incidence of other cancers in Canadian data Nov 25, 2020
New Clinical Strategy for HR-Positive Breast Cancer? Ki67 values before, after preop endocrine therapy associated with recurrence risk Nov 17, 2020
COVID Deaths Drop in the Hospitalized; Miracle Mouthwash? New Organ Discovered A daily roundup of news on COVID-19 and the rest of medicine Oct 21, 2020
No Benefit With Anti-PD-L1 Drug in Metastatic TNBC Lack of progression-free, overall survival boost with atezolizumab contrast with prior trial Sep 22, 2020
Adjuvant Anti-CDK Thwarts Early Breast Cancer Recurrence Risk of invasive recurrence declines 25% in patients with high-risk disease Sep 20, 2020
Newly Approved Drug Boosts Survival in Metastatic TNBC Antibody-drug conjugate as third-line option improved survival, response rates Sep 20, 2020
Skip Chemo for Older Patients With HER2+ Breast Cancer? Less than one-month survival loss at 3 years with trastuzumab monotherapy Sep 18, 2020
Double Mastectomy Linked to Sexual, Body Image Issues in Young Women Pre-op counseling or decision aids could help women make better informed decisions Sep 16, 2020
DCIS Tied to Higher Chance of Breast Cancer Death Black women and those under 40 at particularly high risk Sep 16, 2020
Which Women Choose Hormones for Surgical Menopause? Understanding patterns of use can help improve targeting for education and counseling, researchers say Aug 12, 2020
Survival Effect of pCR Elusive in Breast Cancer 80% lower risk of recurrence with surrogate endpoint, but link to survival unproven Jul 23, 2020
Older Age Should Not Rule Out Chemo in Breast Cancer Patients Providers should consider patient priorities when discussing treatment Jul 17, 2020
The Serious Conversation: Delivering Bad News by Telemedicine As office visits move online, clinicians discuss breaking life-changing diagnoses virtually Jul 13, 2020
Brief Quasi-Fasting Diet Boosts Breast Cancer Chemo Response Randomized trial in neoadjuvant setting Jun 28, 2020
Pembrolizumab May Help in Triple-Negative Breast Cancer Upfront therapy extends progression-free survival in metastatic disease, study shows Jun 01, 2020
Surgery for Metastatic Breast Cancer Fails to Boost Overall Survival Cumulative data, though, don't rule out benefit for selected patients with de novo stage IV disease Jun 01, 2020
Add-On Tucatinib Ups Survival in Breast Cancer With Brain Mets TKI plus trastuzumab-capecitabine reduced risk of death by nearly half Jun 01, 2020
HCQ Linked to Harm in Cancer Patients Combination with azithromycin associated with three-fold risk of mortality, registry study shows May 28, 2020
End of Life and COVID-19; DCIS Doubles Cancer Risk; Training for 'Bad News' News, features, and commentary about cancer-related issues May 28, 2020
New Clue to Anti-PD-L1 Activity in Breast Cancer? Survival benefit with durvalumab in patients with PDL1 copy number alteration May 26, 2020
Five Days of G-CSF Adequate for Breast Cancer Chemo Rate of chemotherapy-induced febrile neutropenia similar to 7- to 10-day regimen May 08, 2020
Honing Chemo Use in Small Breast Tumors Clearest survival benefit for 8-10 mm tumors in HR/HER2-positive disease May 03, 2020
Talzenna Misses OS Endpoint in BRCA-Positive Breast Cancer But PARP inhibitor improved patient-reported outcomes over standard therapy Apr 29, 2020
Anti-PD-L1 Plus PARP Inhibitor Ups Response in Breast Cancer Add-on treatment superior to chemo alone, but questions remain about cost, toxicity Apr 28, 2020
Hormone Levels Tied to Future Breast Cancer Risk "New avenues for exploration" in risk stratification Apr 24, 2020
DOAC Works in Cancer-Related VTE, No Tradeoff in Bleeds Apixaban monotherapy matches dalteparin in non-inferiority trial Mar 29, 2020
Beyond CDK4/6 Inhibitors for HR-Positive Breast Cancer Switching drugs, taking aim at different targets under investigation Mar 11, 2020
Shannen Doherty's Stage IV Breast Cancer "Beverly Hills, 90210" star says she's "petrified" Feb 20, 2020
Bell Ringing Not So Joyous for Cancer Patients? Greater treatment-related distress for those who rang bell at end of treatment Feb 10, 2020
