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Patients treated with semaglutide 7.2 mg weight loss after 72 weeks compared with a reduction of 17.5% with semaglutide 2.4 mg (Wegovy) and 2.4% with placebo, results from the phase IIIb STEP UP trial showed.

Eli Lilly on approval of orforglipron, a once-daily oral GLP-1 receptor agonist for weight loss, by early 2026. (Becker's Hospital Review)

An international panel of 31 experts developed definitions for complete, partial, or absent biochemical and clinical outcomes after . (Lancet Diabetes & Endocrinology)

Unadjusted total calcium measurements are the best and measurements in most clinical settings, a cross-sectional study reported. (JAMA Network Open)

dropped 42%, from $0.33 in 2019 to $0.19 in mid-2024 -- the lowest average recorded in a decade, according to a GoodRx report.

A dietitian defended in Slate.

Here's how President Trump's Greenland plan like some GLP-1 receptor agonists. (New York Times)

A meta-analysis turned up no evidence that use of GLP-1 receptor agonists was tied to over a median follow-up of up to 3 years. (Thyroid)

California Gov. Gavin Newsom's (D) plan to is far behind schedule, industry experts said. (CalMatters)

In related news, a federal law that made companies resulted in smaller discounts for low-income clinics. (New York Times)

Data from continuous glucose monitoring in patients with type 1 diabetes. (Diabetes Technology & Therapeutics)

Excess weight gain in the first trimester of pregnancy was associated with , a prospective cohort study showed. (American Journal of Clinical Nutrition)

A large study of South Korean women found that those who had a higher risk for type 2 diabetes compared with those at ages 50 and older. (JAMA Network Open)

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