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Oncology/Hematology

A close up photo of a womans eye yellowed by jaundice.

Jaundice, Malaise in Woman With Heroin Habit, Inactive Hepatitis B

HDV diagnosis portends imminent cirrhosis despite initial resolution of symptoms

A photo of a senior man in hospital gown sitting in a wheelchair in a hospital hallway.

Testicular Mass Serendipitously Found 12 Years After Prostate Cancer Dx

Consistently low PSA levels failed to signal metastasis

A photo of a senior man smoking a cigarette.

Smoker's Painless Skin Nodules Flag a Fatal Diagnosis

Skin metastasis was the first sign for the otherwise asymptomatic patient

A close up of a mature male sanding a piece of wood.

Rare Tumor in a Rare Location in Patient With Constipation

Could occupational exposure to sawdust explain this case?

A man itches the rash on his forearm

Melanoma Patient on Immunotherapy Develops Severe Dermatitis

Clinicians faced with presumed dermatologic AEs urged to consider all differentials

An illustration of non-invasive bladder cancer

Painless Hematuria Sends 22-Year-Old Man to the Hospital

Unremarkable findings soon led to a remarkable diagnosis

A photo of a boy holding a tablet displaying an xray of his jaw in front of his face.

BRAF Inhibition in Pediatric Ameloblastoma of the Jaw

Targeted therapy in 3 boys allowed for conservative surgery to restore jaw to predisease state

An Asian woman lies in a CT scanner.

Rare Case of Multiple Myeloma in Teenage Girl

Successful use of affordable induction therapy with autologous stem cell transplantation

X-ray of an elderly woman showing pleural effusion of the left lung.

What Is the Cause of Persistent Pleuritis in Lung Cancer Patient?

Diagnosis of exclusion pointed to one agent, 6 months after treatment was completed

A computer rendering of bladder cancer.

Rare Aggressive Bladder Cancer Treated Successfully in Elderly Man

Neoadjuvant chemotherapy followed by cystectomy achieves complete response

A close up of Merkel cell carcinoma on a person鈥檚 arm.

Case: VEGFR Inhibition in Merkel Cell Carcinoma Patient

Disease stabilized after post-chemotherapy progression of the aggressive neuroendocrine cancer

A male physician wearing a protective mask as seen through the chest x-ray he is holding.

Invasive Pneumococcal Disease in Older Man, but There's a Worse Problem

Warning to be alert for this underlying cancer in older patients with bacterial/viral infections

A computer rendering of renal cancer.

Diagnosis of Mass Confined to the Kidney: Is It RCC or TCC?

Ureteroscopy and histopathology should be considered as routine preoperative assessments

Photo of 72-year-old woman being evaluated for mild pain and joint stiffness in her hand.

What's Causing Cancer Patient's Joint Pain While on Checkpoint Inhibitor?

Here is how clinicians diagnosed this rare inflammatory side effect

A close up of a woman wearing a protective mask receiving the COVID-19 vaccine.

Woman Develops Tiny Blood Spots on Her Body After COVID Shot

Case highlights need for quick diagnosis and management of rare disorder

A male physician palpates the swollen thyroid of his young adult female patient.

What Caused This Otherwise Symptom-Free Woman's Neck Mass?

Case shows possible dangers even in hyperfunctioning "hot versus hypofunctioning "cold nodule

CT imaging of primary ameloblastoma with measurement and three-dimensional reconstruction.

Woman Loses 6-Year Battle With Mouth Tumor

Rare ameloblastoma rapidly recurs and metastasizes despite numerous radical excisions

A close up of a female doctor performing an ultrasound on her patients arm.

Teen Develops Persistent, Spreading Arm Swelling After a Fall

Is it "just" a hematoma or something more sinister?

A micrograph of clear cell renal cell carcinoma

How Did a Patient Survive a Decade With Metastatic RCC?

Surgery had beneficial role

A mature woman with her hands on her chest experiencing pain

What's Behind the Mysterious Chest Pain in Bladder Cancer Patient?

Cardiomyopathy risks interrupting cancer treatment, worsening prognosis

Urography showing a large polypoid mass in the bladder

What to Do With a Rare, Aggressive Bladder Cancer

Case authors lament scant information on treatments or outcomes

A mature man holds his painful right buttock

Where Did This Very Painful Gluteal Mass Come From?

High clinical suspicion, low threshold for biopsy key to diagnosis

A computer rendering of a transparent body with a liver with cirrhosis highlighted

Word of Caution on Angiogenesis Inhibitor for Liver Cancer

Case report highlights risk of serious adverse effects

A CT scan showing a kidney with a tumor

Why Did This Cancer Metastasize to the Pancreas?

Although very aggressive, regular CT follow-up can make a difference

A CT scan of bladder cancer

What Caused This Young Man's Bladder Cancer

Occupational exposure, family history make tempting hypotheses

A male physician about to perform an ultrasound on a young male patient

Here's Why Hematuria in a Young Patient Should Always Be Investigated

Terminology also makes a difference

A young Black woman lies on an examination table while a doctor palpates her stomach.

Liver Failure or Liver Mets?

Diagnosis complicated by absence of radiologic evidence of hepatic lesions

A photo of a shingles rash on a man鈥檚 back

Shingles Recurrence or Something Worse?

Bedside skin punch biopsy proved crucial

A mature male with shoulder pain consults with a female healthcare worker

A Sinister Etiology for Shoulder Pain

Patient presented with what was assumed to be rotator cuff injury

A male doctor performs an ultrasound on a pregnant woman

Why Does This Pregnant Woman Have Rectal Bleeding?

Getting a diagnosis was crucial, but options were limited for safe investigation

Macroscopic images of the mass, showing a yellow, greasy, and lobulated surface.

Benign or Malignant? No Way to Tell Radiologically

Case shows importance of accurate preop diagnosis

A woman receiving a CT scan

A Case of Progressive Abdominal Pain Leads to a Surprise Finding

There is ongoing debate about the best approach for this rare diagnosis

A senior woman experiencing back pain

Did Breast Cancer Radiation Cause This Weird Lung Problem?

Especially peculiar since the patient had no risk factors

A man with a pained expression touches his jaw

This Unusual Syndrome of the Face Could Be an Early Sign of AML

Case started with severe pain and numbness

A man clutches his chest in pain which is highlighted in red

Pleuritic Chest Pain, Other Vague Symptoms -- What Could It Be?

Medical sleuthing found rare, potentially deadly disease

A photo of a gelatinous, tumorous lesion and inflammation on a woman's eye

What Is Causing These Disturbing Changes in a Young Woman's Eye?

Inflamed gelatinous lesion unresponsive to topical corticosteroids and antibiotic eye drops

A lump found during the ultrasound examination.

Breast Mass Isn't Cancer, but Why Is It Growing So Quickly?

Hint: check the hormonal involvement

A photo of a woman with a swollen chin taken from two angles

What Is Causing This Woman's Swollen Chin?

A long and challenging diagnostic path with twists and turns

A senior woman with stomach pain grimaces and wraps her arms around her middle

The Diagnostic Challenge of Late Breast Cancer Recurrence

Case illustrates the difficulties

An illustration of a mans face before and during a stroke

What Caused Ischemic Stroke in Healthy 51-Year-Old?

Problem was not really cardiovascular in origin

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